Publications

34.   Iwata, M., Watanabe, S., Yamane, A., Miyasaka, T., and Misonou, H. (2018) Regulatory mechanisms for the axonal localization of tau in neurons. Biorxiv. https://www.biorxiv.org/content/early/2018/11/04/456608

33.   Kubo, A., Ueda, S., Yamane, A., Wada-Kakuda, S., Matsuyama, M., Nomori, A., Takashima, A., Goto, M., Ito, M., Tomiyama, T., Mori, H., Ihara, Y., Misonou, H., and Miyasaka, T. (2018). Ectopic expression induces abnormal somatodendritic distribution of tau in the mouse brain. Biorxiv. https://www.biorxiv.org/content/early/2018/11/06/457853

32.   Kubo, A., Misonou, H., Matsuyama, M., Nomori, A., Wada-Kakuda, S., Takashima, A., Kawata, M., Ihara, Y., and Miyasaka, T. (2018) Distribution of endogenous normal tau in the mouse brain. J. Comp. Neurol., in press.

31.   Hirono, M., Watanabe, S., Karube, F., Fujiyama, F., Kawahara, S., Nagao, S., Yanagawa, Y., and Misonou, H. (2018) Perineuronal nets in the deep cerebellar nuclei regulate GABAergic transmission and delay eyeblink conditioning. J. Neurosci. 38, 6130-6144.

30.    Misonou, H. (2017) Precise localizations of voltage-gated sodium and potassium channels in neurons. Dev. Neurobiol. 78, 271-282.

29.    Jensen, C.S., Watanabe, S., Stas, J.I., Klaphaak, J., Yamane, A., Schmitt, N., Olesen, S.P.O., Trimmer, J.S., Rasmussen, H.B., and Misonou, H. (2017) Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Non-Conventional Secretory Pathway. J. Neurosci. 37, 11523-11536.

28.   Hirono, M. Nagao, S., Yanagawa, Y., and Konishi, S. (2017) Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells. Neuropharmacology 118, 79-89.

27.    Egashira, Y., Takase, M., Watanabe, S., Ishida, J., Fukamizu, A., Kaneko, R., Yanagawa, Y., Takamori, S. (2016) Unique pH dynamics in GABAergic synaptic vesicles illuminates the mechanism and kinetics of GABA loading. Proc. Natl. Acad. Sci. USA 113, 10702-10707.

26.    Watanabe, S., and Hirono, M. (2016) Phase-Dependent Modulation of Oscillatory Phase and Synchrony by Long-Lasting Depolarizing Inputs in Central Neurons.. eNeuro 3.

25.    Bishop, H.I., Guan, D., Bocksteins, E., Parajuli, L.K., Murray, K.D., Cobb, M.M., Misonou, H., Zito, K., Foehring, R.C., and Trimmer, J.S. (2015) Distinct, cell- and layer-specific expression patterns and independent regulation of Kv2 channel subtypes in cortical pyramidal neurons. J. Neurosci. 35, 14922-14942.

24.    Hirono, M., Ogawa, Y., Misono, K., Zollinger, D.R., Trimmer, J.S., Rasband, M.N., and Misonou, H. (2015) BK channels localize to the paranodal junction and regulate action potentials in myelinated axons of cerebellar Purkinje cells. J. Neurosci. 35, 7082-7094.

23.    Hsiao, J.J., Ng, B.H., Smits, M.M., Wang, J., Jasavala, R.J., Martinez, H.D., Lee, J., Alston, J.J., Misonou, H., Trimmer, J.S., and Wright, M.E. (2015) Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility. BMC Cancer 15, 204.

22.    Trimmer, J.S. and Misonou H. (2015) Phosphorylation of voltage-gated ion channels. In Handbook of Ion Channels (M Trudeau and J Zhang ed). Boca Raton: CRC Press. 

21.    Jensen, C.S. and Misonou H. (2015) Live-cell imaging of post-Golgi transport vesicles in cultured hippocampal neurons. Cell. Mol. Neurobiol. 35, 123-135.

20.    Jensen, C.S., Watanabe, S., Rasmussen, H.B., Schmitt, N., Olesen, S.P., Frost, N.A., Blanpied, T.A., and Misonou H. (2014) Specific Sorting and Post-Golgi trafficking of Dendritic Potassium Channels in Living Neurons. J. Biol. Chem. 289, 10566-10581.

19.    Kubota, H., Nagao, S. Obata, K., and Hirono, M.  (2014) mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein -dependent and Src-ERK1/2-dependent signaling pathways. PLoS ONE 9, e106316. Abstract

18.    Hirono, M., Nagao, S., Obata, K. (2014) Developmental α₂-adrenergic regulation of noradrenergic synaptic facilitation at cerebellar GABAergic synapses. Neuroscience 256, 242-251. Abstract

17.    Nomura, T., Watanabe, S., Kaneko, K., Yamanaka, K., Nukina, N., Furukawa, Y. (2014) Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis. J. Biol. Chem. 289, 1192-202. Abstract

16.    Hermanstyne, T.O., Subedi, K., Li, W.W., Hoffman, G.E., Meredith, A.L., Mong, J.A., and Misonou, H. (2013) Kv2.2: A novel molecular target to study the role of basal forebrain GABAergic neurons in the sleep-wake cycle. Sleep 36, 1839-1848.

15.   Hisatsune, C., Miyamoto, H., Hirono, M., Yamaguchi, N., Sugawara, T., Ogawa, N., Ebisui, E., Ohshima, T., Yamada, M., Hensch, TK., Hattori, M., Mikoshiba, K. (2013) IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice. Front. Neural. Circuits 7, 156. Abstract

14.    Sugawara, T., Hisatsune, C., Le, T.D., Hashikawa, T., Hirono, M., Hattori, M., Nagao, S., Mikoshiba, K. (2013) Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of purkinje cells in adult mice. J. Neurosci. 33, 12186-96. Abstract

13.    Kishimoto, Y, Hirono, M, Atarashi, R, Sakaguchi, S, Yoshioka, T, Katamine, S, Kirino, Y (2013) Age-dependent impairment of eyeblink conditioning in prion protein-deficient mice. PLoS ONE 8, e60627. Abstract

12.     Furukawa, Y., Kaneko, K., Watanabe, S., Yamanaka, K., Nukina, N. (2013) Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis. FEBS Lett. 587, 2500-2505. Abstract

11.    Watanabe, S., Kaneko, K., Yamanaka, K. (2013) Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked mutant TDP-43 proteins. J. Biol. Chem. 288, 3641-3654. Abstract

10.    Jensen, C.S., Rasmussen, H.B, and Misonou, H. (2011) Neuronal trafficking of voltage-gated potassium channels. Mol. Cell. Neurosci. 48, 288-297. Abstract

9.   Hermanstyne, T.O., Kihira, Y., Misono, K., Deitchler, A., Yanagawa, Y., and Misonou, H. (2010) Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice. J. Comp. Neurol. 518, 4298-4310 Abstract.

8.    Kihira, Y., Hermanstyne, T.O., and Misonou, H. (2010) Formation of heteromeric Kv2 channels in mammalian brain neurons. J. Biol. Chem. 285, 15048-15055 Abstract.

7.    Misonou, H. (2010) Homeostatic Regulation of Neuronal Excitability by K+ Channels in Normal and Diseased Brains.  The Neuroscientist 16, 51-64 Abstract.

6.    Misonou, H., and Trimmer, J.S. (2009) The diverse roles of K+ channels in brain ischemia. In New strategy in stroke intervention. (L. Annunziato, ed.) pp. 211-224. New York: Springer. 

5.    Mohapatra, D.P., Misonou, H., Pan, S-J., Held, J.E., Surmeier, D.J., and Trimmer, J.S. (2009) Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the KV2.1 potassium channel. Channels 3, 46-56. Abstract.

4.   Misonou, H.*, Thompson, S.M., and Cai, X. (2008) Dynamic regulation of the Kv2.1 voltage-gated potassium channel during brain ischemia through neuroglial interaction. J. Neurosci. 28, 8529-8538. Abstract           

3.    Menegola, M., Misonou, H., Vacher, H., and Trimmer, J.S. (2008) Dendritic A-type potassium channel subunit expression in CA1 hippocampal interneurons. Neuroscience 154, 953-964. Abstract.

2.    Rasmussen, H.B., Frøkjær-Jensen, C., Jensen, C.S., Jensen, H.S., Jørgensen, N.K., Misonou, H., Trimmer, J.S., Olesen, S.P., and Schmitt, N. (2007) Requirement of subunit co-assembly and ankyrin-G for M channel localization at the axon initial segment.  J. Cell Sci. 120, 953-963. Abstract

1.  Schulz, D.J., Baines, R.A., Hempel, C.M., Li, L., Liss, B., and Misonou, H. (2006) Cellular excitability and the regulation of functional neuronal identity: from gene expression to neuromodulation. J. Neurosci. 26, 10362-10367. Abstract

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